Table of Contents
ISRN Gastroenterology
Volume 2011, Article ID 951686, 5 pages
http://dx.doi.org/10.5402/2011/951686
Research Article

Prevalence of Exocrine Pancreatic Insufficiency in Women with Obesity Syndrome: Assessment by Pancreatic Fecal Elastase 1

1Department of Gastroenterology, Endocrinology, and Diabetology, Klinikum Lüdenscheid, 58515 Lüdenscheid, Germany
2Department of Internal Medicine, Medical Clinic C, 67063 Ludwigshafen, Germany
3Department of Rheumatology, Osteology and Physical Therapy, William G. Kerckhoff Foundation, Justus Liebig University Giessen, 35385 Giessen, Germany

Received 4 August 2011; Accepted 13 September 2011

Academic Editor: C. Sperti

Copyright © 2011 J. Teichmann et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. F. Holick, “Vitamin D Status: measurement, interpretation, and clinical application,” Annals of Epidemiology, vol. 19, no. 2, pp. 73–78, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. S. J. Parikh, M. Edelman, G. I. Uwaifo et al., “The relationship between obesity and serum 1,25-dihydroxy vitamin D concentrations in healthy adults,” Journal of Clinical Endocrinology and Metabolism, vol. 89, no. 3, pp. 1196–1199, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. J. Teichmann, S. T. Mann, H. Stracke et al., “Parathormone levels and vitamin D metabolism in female patients with various grades of fecal elastase 1 deficiency,” European Journal of Medical Research, vol. 13, no. 12, pp. 563–567, 2008. View at Google Scholar · View at Scopus
  4. S. T. W. Mann, H. Stracke, U. Lange, H. U. Klör, and J. Teichmann, “Vitamin D3 in patients with various grades of chronic pancreatitis, according to morphological and functional criteria of the pancreas,” Digestive Diseases and Sciences, vol. 48, no. 3, pp. 533–538, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. C. Löser, A. Möllgaard, and U. R. Fölsch, “Faecal elastase 1: a novel, highly sensitive, and specific tubeless pancreatic function test,” Gut, vol. 39, no. 4, pp. 580–586, 1996. View at Google Scholar · View at Scopus
  6. T. Bozkurt, U. Braun, S. Leferink, G. Gilly, and G. Lux, “Comparison of pancreatic morphology and exocrine functional impairment in patients with chronic pancreatitis,” Gut, vol. 35, no. 8, pp. 1132–1136, 1994. View at Google Scholar · View at Scopus
  7. J. E. Dominguez-Munoz, C. Hieronymus, T. Sauerbruch, and P. Malfertheiner, “Fecal elastase test: evaluation of a new noninvasive pancreatic function test,” American Journal of Gastroenterology, vol. 90, no. 10, pp. 1834–1837, 1995. View at Google Scholar · View at Scopus
  8. B. Glasbrenner, A. Schön, S. Klatt, K. Beckh, and G. Adler, “Clinical evaluation of the faecal elastase test in the diagnosis and staging of chronic pancreatitis,” European Journal of Gastroenterology and Hepatology, vol. 8, no. 11, pp. 1117–1120, 1996. View at Google Scholar
  9. S. K. Dutta, M. P. Bustin, R. M. Russell, and B. S. Costa, “Deficiency of fat-soluble vitamins in treated patients with pancreatic insufficiency,” Annals of Internal Medicine, vol. 97, no. 4, pp. 549–552, 1982. View at Google Scholar · View at Scopus
  10. J. B. Dibble, P. Sheridan, and M. S. Losowsky, “A survey of vitamin D deficiency in gastrointestinal and liver disorders,” Quarterly Journal of Medicine, vol. 53, no. 209, pp. 119–134, 1984. View at Google Scholar · View at Scopus
  11. T. Nakamura, K. Takebe, K. Imamura et al., “Fat-soluble vitamins in patients with chronic pancreatitis (pancreatic insufficiency),” Acta Gastro-Enterologica Belgica, vol. 59, no. 1, pp. 10–14, 1996. View at Google Scholar · View at Scopus
  12. C. E. Moran, E. G. Sosa, S. M. Martinez et al., “Bone mineral density in patients with pancreatic insufficiency and steatorrhea,” American Journal of Gastroenterology, vol. 92, no. 5, pp. 867–871, 1997. View at Google Scholar · View at Scopus
  13. A. B. Haaber, A. M. Rosenfalck, B. Hansen, J. Hilsted, and S. Larsen, “Bone mineral metabolism, bone mineral density, and body composition in patients with chronic pancreatitis and pancreatic exocrine insufficiency,” International Journal of Pancreatology, vol. 27, no. 1, pp. 21–27, 2000. View at Google Scholar · View at Scopus
  14. P. D. Hardt, A. Krauss, L. Bretz et al., “Pancreatic exocrine function in patients with type 1 and type 2 diabetes mellitus,” Acta Diabetologica, vol. 37, no. 3, pp. 105–110, 2000. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Arnlöv, J. Sundström, E. Ingelsson, and L. Lind, “The impact of body mass index and the metabolic syndrome on the risk of diabetes in middle-aged men,” Diabetes Care, vol. 34, no. 1, pp. 61–65, 2011. View at Google Scholar
  16. J. Dufner, U. Jensen, and E. Schumacher, Statistik mit SAS, Teubner, Stuttgart, 1st edition, 1992.
  17. L. Sachs, Angewandte Statistik, Springer, Berlin, Germany, 7th edition, 1997.
  18. J. U. Hahn, W. Kerner, P. Maisonneuve, A. B. Lowenfels, and P. G. Lankisch, “Low fecal elastase 1 levels do not indicate exocrine pancreatic insufficiency in type-1 diabetes mellitus,” Pancreas, vol. 36, no. 3, pp. 274–278, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. A. C. Nunes, J. M. Pontes, A. Rosa, L. Gomes, M. Carvalheiro, and D. Freitas, “Screening for pancreatic exocrine insufficiency in patients with diabetes mellitus,” American Journal of Gastroenterology, vol. 98, no. 12, pp. 2672–2675, 2003. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. Twersky and S. Bank, “Nutritional deficiencies in chronic pancreatitis,” Gastroenterology Clinics of North America, vol. 18, no. 3, pp. 543–565, 1989. View at Google Scholar · View at Scopus
  21. E. P. DiMagno, V. L. Go, and W. H. Summerskill, “Relations between pancreatic enzyme ouputs and malabsorption in severe pancreatic insufficiency,” New England Journal of Medicine, vol. 288, no. 16, pp. 813–815, 1973. View at Google Scholar · View at Scopus
  22. E. L. Krawatt, E. B. Maner, and M. Davies, “Absorption of vitamin D and 25-OH vitamin D in patients with intestinal malabsorption,” in Basic Research and its Clinical Application, A. W. Norman, K. Schaefer, and D. V. Herrath, Eds., pp. 975–978, Gruyter, Berlin, Germany, 1st edition, 1979. View at Google Scholar
  23. A. Sziegoleit and D. Linder, “Studies on the sterol-binding capacity of human pancreatic elastase 1,” Gastroenterology, vol. 100, no. 3, pp. 768–774, 1991. View at Google Scholar · View at Scopus
  24. F. M. Hannan, A. Fairney, and D. G. Johnston, “Vitamin D deficiency masking primary hyperparathyroidism,” Annals of Clinical Biochemistry, vol. 41, no. 5, pp. 405–407, 2004. View at Publisher · View at Google Scholar · View at Scopus
  25. J. Hjelmesæth, D. Hofsø, E. T. Aasheim et al., “Parathyroid hormone, but not vitamin D, is associated with the metabolic syndrome in morbidly obese women and men: a cross-sectional study,” Cardiovascular Diabetology, vol. 8, article 7, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. S. Rueda, C. Fernández-Fernández, F. Romero, O. J. Martínez de, and J. Vidal, “Vitamin D, PTH, and the metabolic syndrome in severely obese subjects,” Obesity Surgery, vol. 18, no. 2, pp. 151–154, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. A. P. Pitroda, S. S. Harris, and B. Dawson-Hughes, “The association of adiposity with parathyroid hormone in healthy older adults,” Endocrine, vol. 36, no. 2, pp. 218–223, 2009. View at Google Scholar · View at Scopus