International Scholarly Research Notices / 2011 / Article / Tab 1

Research Article

Altered or Impaired Immune Response to Hepatitis B Vaccine in WNIN/GR-Ob Rat: An Obese Rat Model with Impaired Glucose Tolerance

Table 1

Spleen weight, lymphocyte subsets, lymphocyte proliferative response, and serum IgG and IgM levels in 3-month-old WNIN/GR-Ob lean and obese rats.

Immune parameters3 month old WNIN/GR-Ob females
LeanObese

Spleen weight (mg)/g body weight2 ± 0.07*1.3 ± 0.05
Total T cells (%)43.9 ± 1.64*37.0 ± 1.92
T helper cells (%)38.1 ± 1.58*29.1 ± 1.8
T cytotoxic cells (%)14.7 ± 0.916.8 ± 0.48
Total B cells (%)29.5 ± 3.2223.4 ± 1.01
Splenic lymphocyte proliferative response (T/C)11.6 ± 1.957.9 ± 1.85
IgG levels (mg/mL)2.02 ± 0.184*3.01 ± 0.38
IgM levels (μg/mL)16.7 ± 1.24*27.7 ± 2.46

Values are in mean ± SE; * 𝑃 < 0 . 0 5 (significant difference between lean and obese rats).

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