Table of Contents
ISRN Public Health
Volume 2012, Article ID 121697, 7 pages
Clinical Study

The Effects of Two Maternal Vitamin A Supplementation Regimens on Serum Retinol in Postpartum Mothers: A Randomised Controlled Trial in Brazil

1Diretoria de Pesquisas, Instituto de Medicina Integral Professor Fernando Figueira, Caixa Postal 1393, 50070-550 Recife, PE, Brazil
2Departamento de Nutrição, Centro de Ciências da Saúde, Universidade Federal de Pernambuco (UFPE), 50670-901 Recife, PE, Brazil
3Rua Joaquim Marques de Jesus, 86, apto 101, Piedade, 54420-240 Jaboatão dos Guararapes, PE, Brazil

Received 9 July 2012; Accepted 26 July 2012

Academic Editors: S. M. Ahmed and A. R. Mawson

Copyright © 2012 Luciana Marques Andreto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. K. J. West, “Extent of vitamin A deficiency among preschool children and women of reproductive age,” Journal of Nutrition, vol. 32, pp. 2857S–2866S, 2002. View at Google Scholar
  2. R. E. Lopes, K. S. Ramos, C. C. Bressani, K. Arruda, and A. I. Souza, “Prevalência de anemia e hipovitaminose A em puérperas do Centro de Atenção à Mulher do Instituto Materno Infantil Prof. Fernando Figueira, IMIP: um estudo piloto,” Revista Brasileira De Sau'De Materno Infantil, vol. 6, supplement 1, pp. S63–S68, 2006. View at Google Scholar
  3. World Health Organization, Safe Vitamin A Dosage during Pregnancy and Lactation. Recommendations and Report of a Consultation, WHO/ NUT, Geneva, Switzerland, 1998.
  4. G. H. Beaton, R. Martorell, K. A. L'Abbe et al., Effectiveness of Vitamin A Supplementation in the Control of Young Child Morbidity and Mortality in Developing Countries. Final Report To CIDA, University of Toronto, Toronto, Canada, 1993.
  5. W. W. Fawzi, T. C. Chalmers, M. G. Herrera, and F. Mosteller, “Vitamin A supplementation and child mortality: a meta-analysis,” Journal of the American Medical Association, vol. 269, no. 7, pp. 898–903, 1993. View at Publisher · View at Google Scholar · View at Scopus
  6. P. P. Glasziou and D. E. M. Mackerras, “Vitamin A supplementation in infectious diseases: a meta-analysis,” British Medical Journal, vol. 306, no. 6874, pp. 366–370, 1993. View at Google Scholar · View at Scopus
  7. N. van den Broek, R. Kulier, A. M. Gülmezoglu, and J. Villar, “Suplementación con vitamina A durante el embarazo (Revisión Cochrane traducida),” Cochrane Plus. In press
  8. A. L. Rice, R. J. Stoltzfus, A. De Francisco, J. Chakraborty, C. L. Kjolhede, and M. A. Wahed, “Maternal vitamin A or β-carotene supplementation in lactating Bangladeshi women benefits mothers and infants but does not prevent subclinical deficiency,” Journal of Nutrition, vol. 129, no. 2, pp. 356–365, 1999. View at Google Scholar · View at Scopus
  9. A. Sommer and F. R. Davidson, “Assessment and control of vitamin A deficiency: the annecy accords,” Journal of Nutrition, vol. 132, no. 9, pp. 2845S–2850S, 2002. View at Google Scholar · View at Scopus
  10. D. A. Ross, “Recommendations for vitamin A supplementation,” Journal of Nutrition, vol. 131, pp. 2902S–2906S, 2002. View at Google Scholar
  11. L. C. Malaba, P. J. Iliff, K. J. Nathoo et al., “Effect of postpartum maternal or neonatal vitamin A supplementation on infant mortality among infants born to HIV-negative mothers in Zimbabwe,” American Journal of Clinical Nutrition, vol. 81, no. 2, pp. 454–460, 2005. View at Google Scholar · View at Scopus
  12. S. K. Tchum, S. A. Tanumihardjo, S. Newton et al., “Evaluation of vitamin A supplementation regimens in Ghanaian postpartum mothers with the use of the modified-relative-dose-response test,” American Journal of Clinical Nutrition, vol. 84, no. 6, pp. 1344–1349, 2006. View at Google Scholar · View at Scopus
  13. M. K. Darboe, D. I. Thurnham, G. Morgan et al., “Effectiveness of an early supplementation scheme of high-dose vitamin A versus standard WHO protocol in Gambian mothers and infants: a randomised controlled trial,” The Lancet, vol. 369, no. 9579, pp. 2088–2096, 2007. View at Publisher · View at Google Scholar · View at Scopus
  14. R. A. Ayah, D. L. Mwaniki, P. Magnussen et al., “The effects of maternal and infant vitamin A supplementation on vitamin A status: a randomised trial in Kenya,” British Journal of Nutrition, vol. 98, no. 2, pp. 422–430, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. B. Kirkwood and J. Sterne, Essential Medical Statistics, Blackwell Science, Oxford, UK, 2nd edition, 2003.
  16. H. Flores, M. N. A. Azevedo, F. A. C. S. Campos et al., “Serum vitamin A distribution curve for children aged 2–6 y known to have adequate vitamin A status: a reference population,” American Journal of Clinical Nutrition, vol. 54, no. 4, pp. 707–711, 1991. View at Google Scholar · View at Scopus
  17. H. C. Furr, A. J. Clifford, and A. D. Jones, “Analysis of apocarotenoids and retinoids by capillary gas chromatography-mass spectrometry,” Methods in Enzymology, vol. 213, pp. 281–290, 1992. View at Publisher · View at Google Scholar · View at Scopus
  18. E. Accioly and S. Souza-Queiróz, “Deficiencia de vitamina A en embarazadas asistidas en una maternidad pública en Rio de Janeiro, Brasil,” Rev Chilena Nutrición, vol. 27, pp. 352–357, 2001. View at Google Scholar
  19. E. Casanueva, R. Valdés-Ramos, F. Pfeffer, A. Ricalde-Moreno, E. García-Villegas, and C. Meza, “Serum retinol in urban Mexican women during the perinatal period,” Salud Publica de Mexico, vol. 41, supplement 4, pp. 317–321, 1999. View at Google Scholar · View at Scopus
  20. A. Rice, “Postpartum vitamin A supplementation: evaluating the evidence for action,” A2Z Project Technical Brief, 2007,
  21. P. H. Rondó, B. S. Villar, and A. M. Tomkins, “Vitamin A status of pregnant women assessed by a biochemical indicator and a simplified food frequency questionnaire,” Archivos Latinoamericanos de Nutricion, vol. 49, no. 4, pp. 322–325, 1999. View at Google Scholar · View at Scopus
  22. R. J. Stoltzfus, M. Hakimi, K. W. Miller et al., “High dose vitamin A supplementation of breast-feeding Indonesian mothers: effects on the vitamin A status of mother and infant,” Journal of Nutrition, vol. 123, supplement 4, pp. 666–675, 1993. View at Google Scholar · View at Scopus
  23. World Health Organization, Iron Deficiency Anaemia: Assessment, Prevention, and Control: a Guide for Programme Managers, World Health Organization, Geneva, Switzerland, 2001.
  24. Z. J. Salas, F. Faz-Cepeda, and L. N. B. Castañón, “Consumo de folatos de mujeres en edad fértil de Apocada, N.L. México,” Revista Salud Publica y Nutrición, vol. 4, no. 4, 2003. View at Google Scholar
  25. U.S. Department of Agriculture, Agricultural Research Service, “USDA Nutrient Data Laboratory,” 2001, Composition of Foods Raw, Processed, Prepared. Nutrient Database for Standard Reference, Release 14.
  26. Institute of Medicine. National, Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline, National Academy Press, Washington, DC, USA, 2002.
  27. Organización Mundial de la Salud, Indicadores Para Evaluar Las Prácticas De Alimentación Del Lactante Y Del Niño Pequeño: Conclusiones De La Reunión De Consenso Llevada a cabo Del 6 Al 8 De Noviembre De 2007, OMS, Washington, DC, USA, 2009.
  28. S. A. Tanumihardjo, “Assessing vitamin A status: past, present and future,” Journal of Nutrition, vol. 134, no. 1, pp. 290S–293S, 2004. View at Google Scholar · View at Scopus
  29. S. K. Roy, A. Islam, A. Molla, S. M. Akramuzzaman, F. Jahan, and G. Fuchs, “Impact of a single megadose of vitamin A at delivery on breastmilk of mothers and morbidity of their infants,” European Journal of Clinical Nutrition, vol. 51, no. 5, pp. 302–307, 1997. View at Google Scholar · View at Scopus
  30. L. H. Allen and M. Haskell, “Estimating the potential for vitamin A toxicity in women and young children,” Journal of Nutrition, vol. 132, no. 9, pp. 2907S–2919S, 2002. View at Google Scholar · View at Scopus