Table of Contents
ISRN Pharmaceutics
Volume 2012, Article ID 125864, 5 pages
Research Article

Antioxidant Activity of β-Glucan

1Faculty of Pharmaceutical Sciences, Hokuriku University, Ho 3, Kanagawa-Machi, Kanazawa 920-1181, Japan
2New Business Promotion Department, ADEKA Corporation, 7-2-35, Higashiogu, Arakawaku, Tokyo 116-8554, Japan

Received 13 October 2011; Accepted 31 October 2011

Academic Editors: J. Lee, A. Melhaoui, and M. Y. Rios

Copyright © 2012 Kyoko Kofuji et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


β-Glucans extracted from barley, which mainly contains β-(1,3-1,4)-D-glucan, are used extensively as supplements and food additives due to their wide biologic activities, including a reduction in blood lipid level. In this study, the antioxidant activity of β-glucan was examined to assess potential new benefits associated with β-glucan, because oxidative stress is considered one of the primary causal factors for various diseases and aging. β-Glucan extracted from barley was found to possess significant antioxidant activity. The amount of antioxidant activity was influenced by different physiologic properties (e.g., structure and molecular size) of β-glucan, which varied depending on the source and extraction method used. The antioxidant activity of β-glucan was significantly higher than that of various polymers that are used as food additives. These results indicate that β-glucan has promise as a polymeric excipient for supplement and food additive with antioxidant and other benefits, which may contribute to enhancing health and beauty.