Table of Contents
ISRN Biomathematics
Volume 2012, Article ID 127492, 10 pages
http://dx.doi.org/10.5402/2012/127492
Research Article

Assessing the Impact of Increasing Antimicrobial Resistance of Vibrio cholerae on the Future Trends of Cholera Epidemic

Department of Mathematics, University of Zimbabwe, P.O. Box MP 167, Harare, Zimbabwe

Received 10 August 2012; Accepted 30 October 2012

Academic Editors: J. Chow, J. Suehnel, and J. H. Wu

Copyright © 2012 Steady Mushayabasa and Claver P. Bhunu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Cholera, an acute intestinal infection caused by the bacterium Vibrio cholerae, remains a major public health problem in many parts of Africa, Asia, and Latin America. A mathematical model is developed, to assess the impact of increasing antimicrobial resistance of Vibrio cholerae on the future trends of the cholera epidemic. Equilibrium states of the model are determined and their stabilities have been examined. The impacts of increasing antimicrobial resistance of Vibrio cholerae on the future trends of cholera epidemic have been investigated through the reproductive number. Numerical results are provided to support analytical findings.