Table of Contents
Volume 2012, Article ID 145127, 14 pages
Clinical Study

Moderate-Intensity Exercise Improves Body Composition and Improves Physiological Markers of Stress in HIV-Infected Men

1Department of Health, Exercise, and Sport Science, The Citadel, 171 Moultrie Street, Charleston, SC 29403, USA
2Department of Exercise Science, Arnold School of Public Health, University of South Carolina, 1300 Wheat Street, Columbia, SC 29208, USA
3College of Nursing, University of Tennessee, 4520 Ivy Rose Drive, Knoxville, TN 37918, USA
4College of Nursing, University of South Carolina, 1601 Greene Street, Columbia, SC 29208, USA
5Department of Health, Kinesiology, and Sports Studies, Coastal Carolina University, P.O. Box 261954, Conway, SC 29528-6054, USA

Received 18 October 2012; Accepted 11 November 2012

Academic Editors: D. Aunis, R. L. D. Machado, and J. Poudrier

Copyright © 2012 Wesley David Dudgeon et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


HIV/AIDS and its treatment often alter body composition and result in poorer physical functioning. The aim of this study was to determine the effects of a moderate-intensity exercise program on body composition and the hormones and cytokines associated with adverse health outcomes. HIV-infected males ( ) were randomized to an exercise group (EX) who completed 6 weeks of moderate-intensity exercise training, or to a nonintervention control group (CON). In pre- and postintervention, body composition was estimated via DXA, peak strength was assessed, and resting blood samples were obtained. There was a decrease in salivary cortisol at wake ( ) in the EX and a trend ( ) for a decrease 1 hour after waking. The EX had a significant increase in lean tissue mass (LTM) ( ) following the intervention. Those in the EX below median body fat (20%) increased LTM ( ) only, while those above 20% decreased fat mass ( ), total fat ( ), and trunk fat ( ), while also increasing LTM ( ). Peak strength increased between 14% and 28% on all exercises in the EX group. These data indicate that 6 weeks of moderate-intensity exercise training can decrease salivary cortisol levels, improve physical performance, and improve body composition in HIV-infected men.