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International Scholarly Research Notices
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2012
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Article
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Tab 3
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Clinical Study
Phase II Study of Gemcitabine and Docetaxel Combination in Patients with Previously Treated Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Table 3
Grade 3-4 toxicity summary statistics for all 33 treated patients.
Grade 3-4 toxicity
𝑁
Events
Point estimate
95% confidence interval
Anemia
33
13
39%
25%
56%
Neutropenia
33
10
30%
17%
47%
Hyponatremia
33
10
30%
17%
47%
Dehydration
33
3
9%
3%
24%
Fatigue
33
3
9%
3%
24%
Dyspnea
33
3
9%
3%
24%
Pneumonia
33
3
9%
3%
24%
Thrombocytopenia
33
2
6%
2%
20%
Febrile neutropenia
33
1
3%
1%
15%
Tachycardia
33
1
3%
1%
15%
Syncope
33
1
3%
1%
15%
Fluid retention
33
1
3%
1%
15%
Mucositis
33
1
3%
1%
15%
Hyperglycemia
33
1
3%
1%
15%
Constipation
33
1
3%
1%
15%
Anorexia
33
1
3%
1%
15%
Vomiting
33
1
3%
1%
15%
Other nonhematologic toxicity
33
1
3%
1%
15%