International Scholarly Research Notices / 2012 / Article / Fig 1

Research Article

C-Peptide Reduces Mitochondrial Superoxide Generation by Restoring Complex I Activity in High Glucose-Exposed Renal Microvascular Endothelial Cells

Figure 1

(a) State 3 respiration is the slope of measured O2 consumption in the presence of glutamate-malate and ADP. *, significantly different than low-glucose and high-glucose + C-peptide ( 𝑃 < 0 . 0 2 ). (b) State 4 respiration is the slope of measured O2 consumption after ADP depletion. (c) RCR is the ratio of state 3 to state 4 respiration. *, significantly less than low-glucose and high-glucose + C-peptide (* 𝑃 < 0 . 0 0 0 1 ). 𝑛 = 8 experiments. Data represent mean ± SEM.
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(a)
162802.fig.001b
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