International Scholarly Research Notices / 2012 / Article / Fig 3

Research Article

C-Peptide Reduces Mitochondrial Superoxide Generation by Restoring Complex I Activity in High Glucose-Exposed Renal Microvascular Endothelial Cells

Figure 3

(a) Representative histograms of MitoSOX Red flow cytometry data at 24 hrs. ๐‘Œ -axes represent the number of counts of cells that emit fluorescence. ๐‘‹ -axes represent the average fluorescence intensity of cells. (a1) represents treatment conditions; (a2) represent vehicle control and positive control. (b) Fold-change of mean fluorescence intensity of cells, including the control of low-glucose + antimycin. *, significantly different than low-glucose and high-glucose + C-peptide ( ๐‘ƒ < 0 . 0 0 0 1 ). #, significantly different than high-glucose and low-glucose + antimycin ( ๐‘ƒ < 0 . 0 0 0 1 ).

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