162802.fig.003a
(a)
162802.fig.003b
(b)
Figure 3: (a) Representative histograms of MitoSOX Red flow cytometry data at 24 hrs. 𝑌 -axes represent the number of counts of cells that emit fluorescence. 𝑋 -axes represent the average fluorescence intensity of cells. (a1) represents treatment conditions; (a2) represent vehicle control and positive control. (b) Fold-change of mean fluorescence intensity of cells, including the control of low-glucose + antimycin. *, significantly different than low-glucose and high-glucose + C-peptide ( 𝑃 < 0 . 0 0 0 1 ). #, significantly different than high-glucose and low-glucose + antimycin ( 𝑃 < 0 . 0 0 0 1 ).