Research Article

Unusual Effects of Nicotine as a Psychostimulant on Ambulatory Activity in Mice

Figure 5

Effects of combined administrations of 10 mg/kg of BUP with 0.031–0.125 mg/kg of HAL (a), 0.0625–0.25 mg/kg of FLU (b), or 0.25–2 mg/kg of NIC (c) or combined administration of 4 mg/kg of MP with 0.25–2 mg/kg of NIC (d) on ambulatory activity in ICR mice. Filled columns represent mean values of ambulatory activity for 60 min after the administrations, and vertical lines indicate SEM. (a) 𝑁 = 20–40, (b) 𝑁 = 30–50, (c) 𝑁 = 20–80, and (d) 𝑁 = 20–40. * 𝑃 < 0 . 0 5 compared with BUP + saline or MP + saline.
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(b)
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(c)
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(d)