Table of Contents
ISRN Obstetrics and Gynecology
Volume 2012, Article ID 183403, 5 pages
Clinical Study

Efficacy and Tolerability of Fitostimoline (Vaginal Cream, Ovules, and Vaginal Washing) and of Benzydamine Hydrochloride (Tantum Rosa Vaginal Cream and Vaginal Washing) in the Topical Treatment of Symptoms of Bacterial Vaginosis

1Department of Obstetrics and Gynecology, University Hospital, 4121 Modena, Italy
2Unità Operativa Complessa del Dipartimento Materno Infantile, Azienda Sanitaria Locale Napoli 1, Distretto Sanitario No. 50, Miano, 80145 Napoli, Italy
3ISPharm s.r.l., Via dei Pubblici Macelli 194, 55100 Lucca, Italy

Received 27 July 2012; Accepted 2 October 2012

Academic Editors: F. M. Reis and K. Yang

Copyright © 2012 F. Boselli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. M. Brotman, “Vaginal microbiome and sexually transmitted infections: an epidemiological perspective,” The Journal of Clinical Investigation, vol. 121, pp. 4610–4617, 2011. View at Google Scholar
  2. J. M. Marrazzo, “Interpreting the epidemiology and natural history of bacterial vaginosis: are we still confused?” Anaerobe, vol. 17, pp. 186–190, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. G. Donders, “Diagnosis and management of bacterial vaginosis and other types of abnormal vaginal bacterial flora: a review,” Obstetrical and Gynecological Survey, vol. 65, no. 7, pp. 462–473, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. K. A. Fethers, C. K. Fairley, J. S. Hocking, L. C. Gurrin, and C. S. Bradshaw, “Sexual risk factors and bacterial vaginosis: a systematic review and meta-analysis,” Clinical Infectious Diseases, vol. 47, no. 11, pp. 1426–1435, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Faro and L. E. Phillips, “Non-specific vaginitis or vaginitis of undetermined aetiology,” International Journal of Tissue Reactions, vol. 9, no. 2, pp. 173–177, 1987. View at Google Scholar · View at Scopus
  6. P. Martini, C. Mazzatenta, and G. Saponati, “Efficacy and tolerability of Fitostimoline in two different forms (soake gauzes and cream) and Citrizan gel in the topical treatment of second-degree superficial cutaneous burns,” Dermatology Research and Practice, vol. 2011, Article ID 978291, 8 pages, 2011. View at Publisher · View at Google Scholar
  7. G. Mollica, G. Bonaccorsi, R. Martinello, and D. G. Minale, “Evaluation of efficacy and tolerability of fitostimoline vaginal cream (damor farmaceutici) in the treatment of vaginal inflammation and vulvar dystrophy: a double-blind randomized controlled trial,” Gazzetta Medica Italiana Archivio per le Scienze Mediche, vol. 167, no. 3, pp. 87–95, 2008. View at Google Scholar
  8. W. A. Mahon and M. De Gregorio, “Benzydamine: a critical review of clinical data,” International Journal of Tissue Reactions, vol. 7, no. 3, pp. 229–235, 1985. View at Google Scholar · View at Scopus
  9. C. Pullè and E. Sturlese, “Clinical trial comparing the activity and efficacy of Ibuprofen isobutanolammonium vs Benzydamine hydrochloride, applied as vaginal irrigations, in patients with vaginitis,” Clinical and Experimental Obstetrics and Gynecology, vol. 29, no. 3, pp. 173–179, 2002. View at Google Scholar · View at Scopus
  10. C. S. Bradshaw, A. N. Morton, J. Hocking et al., “High recurrence rates of bacterial vaginosis over the course of 12 months after oral metronidazole therapy and factors associated with recurrence,” Journal of Infectious Diseases, vol. 193, no. 11, pp. 1478–1489, 2006. View at Publisher · View at Google Scholar · View at Scopus