Research Article

Urine from Sexually Mature Intact Male Mice Contributes to Increased Cardiovascular Responses during Free-Roaming and Restrained Conditions

Figure 1

The changes in the hypertensive (a), heart rate (b), and locomotor activity (c) responses of male mice to urine from sexually mature intact (SMI), urine from castrated mice, urine from SMI with terazosin pretreatment, and physiological saline. Indicates a significant difference in the responses to SMI when compared to all groups. # Indicates a significant difference in the responses between the saline treated group when compared to urine from castrated mice and SMI + terazosin pretreated groups. Indicates a significant difference in the responses between saline treated group when compared to SMI Urine, urine from castrated mice, and SMI + terazosin pretreatment ( 𝑃 < 0 . 0 5 ).
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(a)
185461.fig.001b
(b)
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(c)