Comparison of LC-MS Assay and HPLC Assay of Busulfan in Clinical Pharmacokinetics Studies

Figure 2

Representative LC-MS chromatograms from extractions of blank plasma (a), 250 ng/mL busulfan (m/z 264.2) and 200 ng/mL d8-busulfan (m/z 272.2) (b), and a patient plasma sample (c).

(a)

(b)

(c)