Simultaneous Estimation of Metoprolol Succinate and Olmesartan Medoxomil in Pharmaceutical Formulation by Thin-Layer Chromatographic-Densitometric Method

<table>Spectra comparison of MET and OLM. (<svg height="14.5625" id="M21" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 17.5 14.5625" width="17.5" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,14.5625)">
<g transform="translate(72,-60.35)">
<text transform="matrix(1,0,0,-1,-71.95,63.52)">
<tspan style="font-size: 12.50px; " x="0" y="0">A</tspan>
</text>
<text transform="matrix(1,0,0,-1,-62.92,60.4)">
<tspan style="font-size: 8.75px; " x="0" y="0">1</tspan>
</text>
</g>
</g>
</svg> and <svg height="14.5625" id="M22" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 17.5 14.5625" width="17.5" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,14.5625)">
<g transform="translate(72,-60.35)">
<text transform="matrix(1,0,0,-1,-71.95,63.52)">
<tspan style="font-size: 12.50px; " x="0" y="0">A</tspan>
</text>
<text transform="matrix(1,0,0,-1,-62.92,60.4)">
<tspan style="font-size: 8.75px; " x="0" y="0">2</tspan>
</text>
</g>
</g>
</svg>) Bulk of MET and OLM, (<svg height="14.375" id="M23" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 16.637501 14.375" width="16.637501" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,14.375)">
<g transform="translate(72,-60.5)">
<text transform="matrix(1,0,0,-1,-71.95,63.67)">
<tspan style="font-size: 12.50px; " x="0" y="0">B</tspan>
</text>
<text transform="matrix(1,0,0,-1,-63.61,60.55)">
<tspan style="font-size: 8.75px; " x="0" y="0">1</tspan>
</text>
</g>
</g>
</svg> and <svg height="14.375" id="M24" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 16.637501 14.375" width="16.637501" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,14.375)">
<g transform="translate(72,-60.5)">
<text transform="matrix(1,0,0,-1,-71.95,63.67)">
<tspan style="font-size: 12.50px; " x="0" y="0">B</tspan>
</text>
<text transform="matrix(1,0,0,-1,-63.61,60.55)">
<tspan style="font-size: 8.75px; " x="0" y="0">2</tspan>
</text>
</g>
</g>
</svg>) capsule formulation A and (<svg height="14.6" id="M25" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 16.637501 14.6" width="16.637501" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,14.6)">
<g transform="translate(72,-60.32)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">C</tspan>
</text>
<text transform="matrix(1,0,0,-1,-63.61,60.37)">
<tspan style="font-size: 8.75px; " x="0" y="0">1</tspan>
</text>
</g>
</g>
</svg> and <svg height="14.6" id="M26" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 16.637501 14.6" width="16.637501" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,14.6)">
<g transform="translate(72,-60.32)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">C</tspan>
</text>
<text transform="matrix(1,0,0,-1,-63.61,60.37)">
<tspan style="font-size: 8.75px; " x="0" y="0">2</tspan>
</text>
</g>
</g>
</svg>) capsule formulation B, respectively.</table>

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Figure 4

Figure 4: Simultaneous Estimation of Metoprolol Succinate and Olmesartan Medoxomil in Pharmaceutical Formulation by Thin-Layer Chromatographic-Densitometric Method 

Figure 4 | Simultaneous Estimation of Metoprolol Succinate and Olmesartan Medoxomil in Pharmaceutical Formulation by Thin-Layer Chromatographic-Densitometric Method 