Clinical Study

Prevalence and Antibiotic Susceptibility of Community-Associated Methicillin-Resistant Staphylococcus aureus in a Rural Area of India: Is MRSA Replacing Methicillin-Susceptible Staphylococcus aureus in the Community?

Table 1

Percentage susceptibilities to antimicrobial agents of Staphylococcus aureus.

CiprofloxacinErythromycinClindamycinDoxycyclineGentamicinRifampicinCotrimoxazoleChloramphenicol

CA-SA, % (95% CI)25.2 (18.2–33.8)58.6 (49.4–67.3)87.1 (79.6–92.1)93.7 (87.3–97)74.6 (65.9–81.7)91.4 (82.8–95.9)55.2 (46–64)95.6 (89.8–98.2)
HA-SA, % (95% CI)19.8 (12.4–29.9)62 (50.8–72.1)75.9 (65.2–84.2)83.6 (72.6–90.7)78.2 (67.6–86.1)91.1 (80.1–96.3)58.8 (47.6–69.1)90.9 (82–95.6)
CA-SA versus HA-SA, P value0.3680.6340.0450.030.560.9530.6190.189
CA-MSSA, % (95% CI)42.9 (28.8–58.1)70.7 (55.1–82.6)92.3 (78.5–97.5)97.5 (84–99.7)92.9 (79.9–97.7)89.7 (72.2–96.7)78 (62.8–88.2)92.7 (79.5–97.6)
HA-MSSA, % (95% CI)33.3 (17.5–54.1)82.6 (61.6–93.4)95.7 (74.4–99.4)95 (71.4–99.3)95.7 (74.5–99.4)100 (93.5–81.5)69.6 (48.3–84.8)95.2 (72.5–99.3)
CA-MSSA versus HA-MSSA, P value0.4460.2920.6050.6110.6540.170.4520.698
CA-MRSA, % (95% CI)15.6 (9–25.6)52 (40.7–63.1)84.4 (74.4–91)91.5 (82.3–96.2)64.5 (53–74.5)92.3 (81.1–97.1)42.7 (31.9–54.1)97.3 (89.6–99.3)
HA-MRSA, % (95% CI)14 (7.1–25.8)53.6 (40.5–66.2)67.9 (54.5–78.8)78.7 (64.6–88.2)70.9 (57.5–81.4)87.2 (72.5–94.6)54.4 (41.3–66.9)89.3 (78–95.1)
CA-MRSA versus HA-MRSA, P value0.8030.8590.0240.0460.4390.4170.1820.063
MSSA, % (95% CI)39.4 (28.3–51.7)75 (62.9–84.1)93.5 (83.9–97.6)96.7 (87.5–99.2)93.8 (84.6–97.7)93.5 (81.4–97.9)75 (62.9–84.1)93.5 (83.9–97.6)
MRSA, % (95% CI)14.9 (9.8–22.1)52.7 (44.1–61.1)77.4 (69.5–83.8)86.4 (78.9–91.6)67.2 (58.6–74.7)90.1 (81.9–94.8)47.7 (39.3–56.3)93.8 (88–96.9)
MSSA versus MRSA, P value<0.0010.0030.0060.032<0.0010.51<0.0010.947
CA-MSSA versus CA-MRSA, P value0.0010.050.2310.2160.0010.684<0.0010.252
HA-MSSA versus HA-MRSA, P value0.0460.0160.0090.10.0160.1220.2120.418

CA: community associated; HA: health-care associated; SA: Staphylococcus aureus; MSSA: methicillin-susceptible Staphylococcus aureus; MRSA: methicillin-resistant Staphylococcus aureus; CI: confidence interval.