International Scholarly Research Notices / 2012 / Article / Tab 1

Clinical Study

Wound Healing with Medications for Rheumatoid Arthritis in Hand Surgery

Table 1

Medication groups in 35 hands.

Examples (no. of patients)**Total no. of hands per groupMedication continuedNo. of wound breakdownsNo. of wound infections

NSAIDSDiclofenac (6), ibuprofen (4), flurbiprofen (1), indomethacin (2), naproxen (6), nabumetone (1)20Yes01
Cox-2 InhibitorsCelecoxib, rofecoxib0
BiologicsEtanercept (4)4No00
Gold (1), hydroxychloroquine (2),
sulfasalazine (8)
Cytotoxic DMARDsLeflunomide (1), methotrexate (20), azathioprine (3)24Yes01
AnticoagulantsWarfarin, heparin0
Aspirin***Dose 75–300 mg daily 5Yes00
No medication200

Key: NSAIDs: nonsteroidal anti-inflammatory drugs, Cox-2: cyclo-oxygenase 2 inhibitors, DMARDs: disease modifying antirheumatic drugs.
*General analgesics excluded, for example, paracetamol, nefopam, codeine, morphine.
**Some patients were taking more than one medication in a group.
***Aspirin was used for cardiovascular risk reduction (75–300 mg) rather than analgesia/anti-inflammatory.

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