Application of HPLC for the Simultaneous Determination of Paracetamol, Chlorzoxazone, and Nimesulide in Pharmaceutical Dosage Form

Table 2

Intraday and interday precision of PCM, CHZ, and NIM (𝑛=6).

Drugs Concentration; (μg mL^−1)		Repeatability			Intermediate precision
		found conc. ± SD	% R.S.D.	S.E.	found conc. ± SD	% R.S.D.	S.E.
	32.5	32.65 ± 0.36	1.10	0.15	32.55 ± 0.20	0.61	0.09
PCM	45.5	45.65 ± 0.25	0.55	0.10	45.75 ± 0.45	0.98	0.18
	65.0	65.65 ± 0.55	0.88	0.22	65.20 ± 0.35	0.54	0.14
	37.5	37.75 ± 0.36	0.95	0.14	45.56 ± 0.45	0.98	0.18
CHZ	52.5	52.60 ± 0.20	0.38	0.09	52.75 ± 0.46	0.87	0.19
	75.0	75.50 ± 0.70	0.93	0.29	75.15 ± 0.99	0.86	0.40
	10.0	10.15 ± 0.10	0.99	0.04	10.12 ± 0.17	1.66	0.07
NIM	14.0	14.05 ± 0.18	1.28	0.07	14.97 ± 0.25	1.67	0.10
	20.0	20.08 ± 0.15	0.75	0.06	20.28 ± 0.20	0.98	0.09