Clinical Study

Left Ventricular Hypertrophy Is Associated with Diastolic Filling Alterations in Normotensive Offspring of Hypertensive Nigerians

Table 1

Clinical and echocardiographic parameters in the study group.

Dimension
SubjectsControls
value
Mean (SD)Mean (SD)

Number6565ā€‰
Age (years)21.6 (0.29)21.7 (0.26)0.88
Body mass index (kg/m2)22.1 (3.0)21.7 (2.8)0.41
WC (cm)80.4 (8.9)78.3 (7.1)0.22
Pulse rate (beats/min)76.8 (11.6)74.5 (9.7)0.32
SBP (mmHg)118.2 (9.0)115.9 (8.8)0.14
DBP (mmHg)75.6 (7.6)72.8 (8.8)0.06
RVd (mm)13.3 (4.5)14.3 (3.6)0.14
IVSd (mm)11.2 (2.4)11.2 (2.7)0.97
PWd (mm)9.7 (2.3)8.5 (1.8)0.001*
LVDd (mm)45.6 (5.3)45.4 (5.8)0.8
LVDs (mm)29.2 (6.5)29.1 (4.8)0.92
Ejection fraction (%)66.8 (8.4)65.5 (8.8)0.4
LVM (g)196.9 (63.8)175.2 (58.8) 0.01*
LVMI (g/m2)114.5 (32.6)103.2 (26.1) 0.01*
AOD (mm)27.3 (2.9)27.2 (3.0)0.78
LAD (mm)30.7 (4.5)30.8 (5.0)0.88
RWT0.43 (0.11)0.38 (0.09)0.001*

Key: WC: waist circumference, RVd: right ventricular dimension, IVSd: interventricular septum in diastole, PWd: posterior wall in diastole, LVDd: left ventricular dimension in diastole, LVDs: left ventricular dimension in systole, LVM: left ventricular mass, LVMI: left ventricular mass index, AOD: aortic dimension, LAD: left atrial dimension, and RWT: relative wall thickness. *Statistically significant.