Review Article

The Use of Ketogenic Diet in Pediatric Patients with Epilepsy

Table 1

Types of ketogenic diets [4].

Macronutrient content (% total daily calories) Comments
FatProteinCarbohydrate

(i) 4 : 1 or 3 : 1 (fat : nonfat) ratio
Classic ketogenic diet LCT: 85–90 6–82–4(ii) Unpalatable poor compliance
(iii) GI effects: constipation

(i) ~3 : 1 (fat : nonfat) ratio
MCT dietMCT: 71 1019(ii) Easier to prepare
(iii) Greater flexibility with protein and carbohydrate allowance
(iv) GI effects: nausea, vomiting, diarrhea in ~50% patients

Modified MCT dietLCT: 40–50 10–205–10(i) Incorporates LCT and MCT

MCT: 30
(ii) Fewer GI effects

(i) No fasting or hospital stay
Modified Atkins diet60–70 20–305(ii) No calorie restrictions
(iii) Less dietitian support

Low-glycemic-index treatment diet60–70 20–3010(i) Only low-glycemic-index carbohydrates allowed for 10% daily carbohydrates
(ii) Details of how diet is prescribed are not widely known [1]

LCT: long-chain triglycerides; MCT: medium-chain triglycerides; GI: gastrointestinal.