PP13 and PAPP-A in the First and Second Trimesters: Predictive Factors for Preeclampsia?

Table 7

The validity factors of linear combinations of preeclampsia markers based on the three linear combinations.

Linear combination	Cutoff	Sensitivity; (95% CI)	Specificity %; (95% CI)	Positive predictive value %; (95% CI)	Negative predictive value %; (95% CI)	Surface under curve; (95% CI)
PAPPA1+(PP13_1/10)	≤10.9	86.0; (77.6–91.2)	80.0; (70.8–87.3)	81.1; (72.4–88.1)	85.1; (76.3–91.6)	0.919; (0.884–0.954)
PAPPA2+(PP13_2/3)	≤214.5	89.0; (81.2–94.4)	81.0; (71.9–88.2)	82.4; (73.9–89.1)	88.0; (79.6–93.9)	0.932; (0.886–0.957)
(10×PAPPA1)+PP13_1+(PAPPA2/2)+(PP13_2/4)	≤238.5	91.0; (83.6–95.8)	91.0; (83.6–95.8)	91.0; (83.6–95.8)	91.0; (83.6–95.8)	0.968; (0.949–0.987)