Fluorometric Determination of Drugs Containing α-Methylene Sulfoxide Functional Groups Using 𝑁¹- Methylnicotinamide Chloride as a Fluorogenic Agent

Table 3

Regression analysis parameters for the determination of 1–5 in spiked human plasma samples using the proposed method.

Drug	Linearity range	Slope*		Intercept*		R^2
		Mean	SE	Mean	SE
1	1–50 μg/mL	4.0771	0.023	42.674	0.78	0.994
2	75–1200 ng/mL	0.6673	0.006	16.3935	2.168	0.9949
3	100–1400 ng/mL	0.5084	0.0035	100.731	0.019	0.9971
4	10–1500 ng/mL	0.6283	0.12	67.419	0.39	0.9989
5	50–2100 ng/mL	0.466	0.01	10.3	1.25	0.999

Average of triplicate analyses, 15 calibration data points.
*Three calibrations curves were performed for each drug.