Epicutaneous Immunotherapy Compared with Sublingual Immunotherapy in Mice Sensitized to Pollen (Phleum pratense)
Airway hyperresponsiveness after immunotherapy. Mice were exposed to increasing doses of methacholine the day following the last 30-minute aerosol challenge: (a) dose-response curves and (b) individual area under the curve (AUC) calculated from data of graph (a) Treatment groups were EPIT (epicutaneous immunotherapy), SLIT (sublingual immunotherapy), sham (sensitized not treated), and C (control, not sensitized, and not treated). *, **, ***.
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