Comparison between Fluconazole with Oral Protexin Combination and Fluconazole in the Treatment of Vulvovaginal Candidiasis

Table 2

Absolute and relative frequency distribution of subjects with vulvovaginal candidiasis according to complaints before and after treatment in the two treatment groups (fluconazole-placebo and fluconazole-protexin).

Groups	Fluconazole + placebo					Fluconazole + protexin
Complaints	Index										Intergroup comparison
	Before treatment		After treatment		Intergroup	Before treatment		After treatment		Intragroup
	Total	Percent	Total	Percent	comparison	Total	Percent	Total	Percent	comparison
Vaginal secretion	45	100	5	11.2	—	45	100	2	4.4	—	NS; Fisher
Itching	45	100	7	15.6	—	45	100	7	15.6	—	NS; Chi-square
Dysuria	23	51.1	12	26.7	0.001	21	46.7	4	8.9	0.001	P = 0.02
Pain during intercourse	28	62.2	6	13.4	0.001	22	48.9	8	17.8	0.001	NS; Chi-square
Pain when urinating	9	20	3	6.7	0.031	11	24.4	7	15.6	0.125	NS; Fisher