Distribution of Nidogen in the Murine Eye and Ocular Phenotype of the Nidogen-1 Knockout Mouse
Light microscopic images of a homozygous nidogen-1 knockout mouse. Scale bar equals 50 μm. The morphology of the cornea (a) and ciliary body/iris (b) is not altered. There is no staining for nidogen-1 (c) Descement’s membrane (arrows), ciliary processes (CP), and trabecular meshwork (TM). In the retina (d), small protrusions of neuronal tissue can be seen (arrowhead); the retina shows otherwise no morphological changes. IPL: inner plexiform layer, INL: inner nuclear layer, ONL: outer nuclear layer.
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