Distribution of Nidogen in the Murine Eye and Ocular Phenotype of the Nidogen-1 Knockout Mouse
Electron microscopic views of an optic nerve cross section of a heterozygous (a) and a homozygous (b) nidogen-1 knockout mouse (scale bar equals 10 μm). In the heterozygous mouse, the nerve fibres are regular arranged and the astrocytes in a quiescent stage (asterisk). In the homozygous mouse, the nerve fibres are irregular arranged and the astrocytes appear activated (asterisk).
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