Docking Applied to the Study of Inhibitors of c-Met Kinase
Docking solutions of the compounds 1 (carbon atoms in yellow), 9 (carbon atoms in orange), and 10 (carbon atoms in pink). Important residues of the active site of the kinase were highlighted (in green). Color code for heteroatoms is as follows: fluorine: cyan, nitrogen: blue, sulfur: yellow, oxygen: red, and chlorine: grey. Only one hydrogen atom of MET1160 was shown for simplicity. H-bonding interactions between the molecules and this residue were shown as a dashed line. Distance values are given in Table 1.
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