Docking Applied to the Study of Inhibitors of c-Met Kinase

Figure 4

Docking solutions of the compounds 1 (carbon atoms in yellow), 9 (carbon atoms in orange), and 10 (carbon atoms in pink). Important residues of the active site of the kinase were highlighted (in green). Color code for heteroatoms is as follows: fluorine: cyan, nitrogen: blue, sulfur: yellow, oxygen: red, and chlorine: grey. Only one hydrogen atom of MET1160 was shown for simplicity. H-bonding interactions between the molecules and this residue were shown as a dashed line. Distance values are given in Table 1.