International Scholarly Research Notices

Research Article

Lesions of Acetylcholine Neurons in Refractory Epilepsy

Table 3

Results of the quantitative analysis in the pedunculopontine tegmental nucleus in cases with a history of West syndrome.
 AgeMAP2AchE%AchETH%THCD%CD
Controls ( 𝑛 = 6 )
4 m–38 y
243 (41)
68 (16)
29 (9)
25 (13)
10 (5)
27 (17)
11 (6)
WS/LGS ( 𝑛 = 6 )
5–18 y
181 (39)
12 (15)
8 (12)
35 (10)
19 (5)
18 (20)
9 (10)
WS ( 𝑛 = 6 )5–26 y
184 (38)
29 (39)
13 (18)
27 (18)
16 (10)
31 (14)
17 (8)
Kruskal-Wallis  𝑃 < 0 . 0 5
𝑃 < 0 . 0 5
      
“WS/LGS” and “WS” denote cases with a history of West syndrome (WS) and Lennox-Gastaut syndrome (LGS) and cases with a history of only WS, respectively. All results are presented as the mean (SD), and both the total number of neurons that were immunoreactive for each marker and the percentage of neurons immunoreactive for each marker relative to the total neurons are shown. m: months; y: years; MAP2: microtubule-associated protein 2; AchE: acetylcholinesterase; TH: tyrosine hydroxylase; CD: calbindin-D28K.