A Review of Hot-Melt Extrusion: Process Technology to Pharmaceutical Products

Table 1

Different hot-melt extruded films comprising different polymeric materials, plasticisers, and active ingredients for various indications.

Film	Main polymer(s)	Plasticiser/additive	Main active ingredient(s)	References
1	Acrylic	Triacetin	Lidocaine	Mididoddi and Repka [68]
	Eudragit	Triethylcitrate
2	Hydroxypropylcellulose	N/A	Ketoconazole	Prodduturi et al. [60]
	Polyethylene oxide
3	Hydroxypropylcellulose	Polyethylene glycol 3350	Lidocaine	Repka et al. [61]
	Hydroxypropylmethylcellulose
	Polyethylene oxide
4	Hydroxypropylcellulose	Polyethylene glycol 400	Hydrocortisone	Repka et al. [64]
5	Hydroxypropylcellulose	Polyethylene glycol 3350	Clotrimazole	Repka et al. [58]
	Polycarbophil
6	Polyethylene oxide	N/A	Ketoprofen	Tumuluri et al. [59]