Review Article
A Review of Hot-Melt Extrusion: Process Technology to Pharmaceutical Products
Table 1
Different hot-melt extruded films comprising different polymeric materials, plasticisers, and active ingredients for various indications.
| Film | Main polymer(s) | Plasticiser/additive | Main active ingredient(s) |
References |
| 1 | Acrylic | Triacetin | Lidocaine |
Mididoddi and Repka [68] | Eudragit | Triethylcitrate |
| 2 | Hydroxypropylcellulose | N/A | Ketoconazole |
Prodduturi et al. [60] | Polyethylene oxide |
| 3 | Hydroxypropylcellulose | Polyethylene glycol 3350 | Lidocaine |
Repka et al. [61] | Hydroxypropylmethylcellulose | Polyethylene oxide |
| 4 | Hydroxypropylcellulose | Polyethylene glycol 400 | Hydrocortisone | Repka et al. [64] |
| 5 | Hydroxypropylcellulose | Polyethylene glycol 3350 | Clotrimazole |
Repka et al. [58] | Polycarbophil |
| 6 | Polyethylene oxide | N/A | Ketoprofen | Tumuluri et al. [59] |
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