Synergistic Effect between Maternal Infection and Adolescent Cannabinoid Exposure on Serotonin 5HT_1A Receptor Binding in the Hippocampus: Testing the “Two Hit” Hypothesis for the Development of Schizophrenia

Figure 3

Plasma cytokine (a and b) and corticosterone (c) levels in pregnant dams 2 hours post intravenous (IV) injection with vehicle (VEH) or poly I:C (POLY), or at the point of euthanasia, 27 days after injection (𝑛=4 per group). ^𝜋𝑃=0.012, ^&𝑃=0.005, ⁺𝑃=0.05 compared to PBS treated dams using Student’s 𝑡-test.

(a)

(b)

(c)