International Scholarly Research Notices

Research Article

Synergistic Effect between Maternal Infection and Adolescent Cannabinoid Exposure on Serotonin 5HT1A Receptor Binding in the Hippocampus: Testing the “Two Hit” Hypothesis for the Development of Schizophrenia

Table 2

Two-way ANOVA (treatment × region) of serotonin 5 H T 1 A receptor binding in the CA1 of the hippocampus and somatosensory cortex on postnatal days (PND) 55, 65, and 90 ( 𝑛 = 6–8 per treatment group at each timepoint).
TreatmentRegionTreatment × Region
PND 55 𝐹 ( 3 , 6 3 ) = 1 0 . 0 3 , 𝑃 < 0 . 0 0 0 1 𝐹 ( 2 , 6 3 ) = 8 4 4 . 3 , 𝑃 < 0 . 0 0 0 1 𝐹 ( 6 , 6 3 ) = 1 4 . 2 4 , 𝑃 < 0 . 0 0 0 1
PND 65 𝐹 ( 3 , 6 3 ) = 3 . 5 9 3 , 𝑃 = 0 . 0 1 8 3 𝐹 ( 2 , 6 3 ) = 5 2 9 . 1 , 𝑃 < 0 . 0 0 0 1 𝐹 ( 6 , 6 3 ) = 3 . 3 9 9 , 𝑃 = 0 . 0 0 5 7
PND 90 𝐹 ( 3 , 6 0 ) = 5 . 3 7 0 , 𝑃 = 0 . 0 0 2 4 𝐹 ( 2 , 6 0 ) = 6 6 8 . 3 , 𝑃 < 0 . 0 0 0 1 𝐹 ( 6 , 6 0 ) = 9 . 2 6 2 , 𝑃 < 0 . 0 0 0 1