miR-320 Regulates Glucose-Induced Gene Expression in Diabetes
Figure 3
HUVECs exposed to 25 mM glucose (HG) compared to 5 mM glucose (LG) showed (a) increased FN protein and (b) increased in ET-1 protein. Transfection of endothelial cells with miR-320 mimics (but not the scrambled mimics) reduced glucose induced upregulation of FN and ET-1 protein levels. (S: scrambled miRNA, miR-320: miR-320 mimic, *significantly different from LG, : significantly different from HG).
