Table of Contents
ISRN Hematology
Volume 2012, Article ID 567491, 3 pages
http://dx.doi.org/10.5402/2012/567491
Research Article

Evaluation of the First Commercial Hepcidin ELISA for the Differential Diagnosis of Anemia of Chronic Disease and Iron Deficiency Anemia in Hospitalized Geriatric Patients

1Laboratory Medicine, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium
2Internal Medicine, Division of Geriatric Medicine, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium

Received 11 November 2011; Accepted 8 December 2011

Academic Editor: C. Panizo

Copyright © 2012 Inge Geerts et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. Joosten, W. Pelemans, M. Hiele, J. Noyen, R. Verhaeghe, and M. A. Boogaerts, “Prevalence and causes of anaemia in a geriatric hospitalized population,” Gerontology, vol. 38, no. 1-2, pp. 111–117, 1992. View at Google Scholar · View at Scopus
  2. G. Weiss and L. T. Goodnough, “Anemia of chronic disease,” The New England Journal of Medicine, vol. 352, no. 10, pp. 1011–1023, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  3. E. Joosten, R. Van Loon, J. Billen, N. Blanckaert, R. Fabri, and W. Pelemans, “Serum transferrin receptor in the evaluation of the iron status in elderly hospitalized patients with anemia,” American Journal of Hematology, vol. 69, no. 1, pp. 1–6, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  4. B. A. Barron, J. D. Hoyer, and A. Tefferi, “A bone marrow report of absent stainable iron is not diagnostic of iron deficiency,” Annals of Hematology, vol. 80, no. 3, pp. 166–169, 2001. View at Publisher · View at Google Scholar · View at Scopus
  5. T. Ganz, “Hepcidin and iron regulation, 10 years later,” Blood, vol. 117, no. 17, pp. 4425–4433, 2011. View at Publisher · View at Google Scholar · View at PubMed
  6. T. Ganz, G. Olbina, D. Girelli, E. Nemeth, and M. Westerman, “Immunoassay for human serum hepcidin,” Blood, vol. 112, no. 10, pp. 4292–4297, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  7. L. Ferrucci, R. D. Semba, J. M. Guralnik et al., “Proinflammatory state, hepcidin, and anemia in older persons,” Blood, vol. 115, no. 18, pp. 3810–3816, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  8. I. Theurl, E. Aigner, M. Theurl et al., “Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications,” Blood, vol. 113, no. 21, pp. 5277–5286, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  9. C. Thomas, U. Kobold, S. Balan, R. Roeddiger, and L. Thomas, “Serum hepcidin-25 may replace the ferritin index in the Thomas plot in assessing iron status in anemic patients,” International Journal of Laboratory Hematology, vol. 33, no. 2, pp. 187–193, 2011. View at Publisher · View at Google Scholar · View at PubMed
  10. J. J. C. Kroot, E. H. J. M. Kemna, S. S. Bansal et al., “Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization,” Haematologica, vol. 94, no. 12, pp. 1748–1752, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus