International Scholarly Research Notices / 2012 / Article / Tab 5

Review Article

Targeted Delivery of Nanomedicines

Table 5

Drug targets.

Sl. no.TargetDescription

(1)Folate receptorA folate-binding protein. Folate receptor-targeted epothilone BMS753493 contains an epothilone moiety linked to a single folate molecule. It delivers the antimitotic epothilone component into cells expressing folic acid receptors, frequently unregulated in tumor cells

(2)Peptide receptorA cell surface protein that binds peptides with high affinity

(3)Cell membraneAlso called the plasma membrane, plasmalemma or “phospholipid bilayer”, it is a semipermeable lipid bilayer found in all cells

(4)Cell surface antigenAntigens on surfaces of cells, for example, infectious or foreign cells or viruses; they are usually protein-containing groups on cell membranes or walls.

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