Dose-Painted Intensity Modulated Radiation Therapy Improves Local Control for Locally Advanced Pancreas Cancer
Table 3
Radiation delivery to OARs.
Organ
Mean IMRT value
Mean coplanar 3D-CRT value
Mean noncoplanar 3D-CRT value
P value (coplanar versus noncoplanar 3D-CRT)
value (IMRT versus noncoplanar 3D-CRT)
Right kidney V12 (%)
75.5
75.6
68.9
0.03
0.3
R. kidney V18 (%)
45.5
62.0
58.4
0.6
0.1
Left kidney V12 (%)
69.0
48.3
41.0
0.1
0.001
Left kidney V18 (%)
43.2
35.2
26.4
0.04
0.006
Mean liver dose (Gy)
16.5
20.0
19.5
0.1
0.001
Small bowel V45 (%)
7.1
12.1
12.8
0.01
0.0002
Stomach V45 (%)
8.7
16.6
15.8
0.2
0.007
Max spinal cord dose
35.0
32.0
35.5
0.04
0.8
OAR: organ at risk; IMRT: intensity-modulated radiation Therapy; 3D-CRT: three-dimensional conformal radiation therapy; : volume of an organ receiving Gy.