International Scholarly Research Notices / 2012 / Article / Tab 2

Clinical Study

Computed Three-Dimensional Atlas of Subthalamic Nucleus and Its Adjacent Structures for Deep Brain Stimulation in Parkinson's Disease

Table 2

The chief complaints, clinical effects, and anatomical locations of the stimulated contacts in 11 patients treated with deep brain stimulation.

Case no.UPDRS Localization of stimulated contactAC-PC (mm)RN (mm)AkinesiaTremorGait disturbanceOn-Off (%/day) Dyskinesia (%/day) Levodopa equivalent (mg/day)
RightLeftRightLeft
PrePostPrePostPrePostPrePostPrePostPrePostPrePostPrePost

11910ZIZI224.84000002150207030565468
2269FHFH226.05000004220207030347280
32816ZIFH216.05210204340000533418
43115ZIZI216.081005054600500628400
5194ZISTN206.0212040200000342271
62812STNSTN234.0313130530000396253
74425ZISTN246.01073031530000557590
87360ZIFH255.41072020101070505020503503
9247STNSTN215.6103020433005020570500
104416FHFH216.062303043007020285285
11134ZINo placement245.0100050100000440307
Mean31.716.522.25.551.91.50.12.60.14.22.924.58.232.710.9470388.6
± S.D.16.715.61.60.73.32.61.40.31.70.32.42.727.016.032.313.0113.5116.1

Akinesia: UPDRS II items 9, 10, 11, 12, 13, 14, 15, on-off and percentage of daily time spent in off states, tremor: UPDRS III items 20 and 21, gait disturbance: UPDRS III items 27, 28, 29, and 30, dyskinesia: the percentage of daily time spent in dyskinesia, rigidity: UPDRS III item 22 on the side contralateral to DBS stimulation.
AC-PC: distance of anterior commissure-posterior commissure, RN: lateral distance from the midline of red nucleus, ZI: zona incerta, STN: subthalamic nucleus, FH: field of forel H, and mean ± S.D.: mean ± standard deviation, pre: before surgery, post: after surgery.

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