Research Article

Validated HPTLC Method for Simultaneous Estimation of Atenolol and Aspirin in Bulk Drug and Formulation

Table 2

Robustness testing.

ParameterSD of Peak Area for Atenolol % RSDSD of Peak Area for Aspirin % RSD

Mobile phase composition (±0.1 mL)6.721.0412.381.21
Amount of mobile phase (±5%)8.940.977.820.78
Time from spotting to chromatography (10 min)9.680.8810.970.41
Time from chromatography to scanning (10 min)10.521.159.831.28