Study on Genetic Variance of miR-541 in Type 1 Diabetes
Figure 4
Alteration in the genetic sequence alters the secondary structure of the miR-541 precursor. The RNA secondary structure predicted by RNAfold web server indicated that a change in the secondary structure of miR-541 precursor may alter the base pair match of its precursor root region. Black arrows indicate the change in the sequence and secondary structure. The most stable secondary structure was selected on the basis of minimum free energy (MFE).
