Itraconazole Niosomes Drug Delivery System and Its Antimycotic Activity against Candida albicans
Table 2
Vesicle size of niosomes.
Batch code
Size of niosome in μm
Without shaking VS ± SD*
PI*
With shaking VS ± SD
PI
After sonication VS ± SD
PI
ES60A
31.76 ± 1.41
0.04
28.27 ± 1.52
0.05
22.29 ± 1.96
0.08
ES60B
33.19 ± 1.42
0.04
30.17 ± 1.98
0.06
23.41 ± 1.52
0.06
ES60C
35.88 ± 1.96
0.05
31.39 ± 0.96
0.03
25.82 ± 2.22
0.08
ES60D
24.10 ± 1.49
0.06
21.30 ± 1.06
0.05
16.02 ± 1.35
0.08
ES60E
26.38 ± 1.52
0.05
23.84 ± 1.79
0.07
17.06 ± 1.16
0.06
ES60F
29.00 ± 1.22
0.04
25.55 ± 1.16
0.04
21.20 ± 1.17
0.05
ES60G
20.13 ± 2.33
0.11
16.67 ± 1.76
0.10
12.46 ± 0.78
0.06
ES60H
22.31 ± 2.30
0.10
19.96 ± 2.19
0.11
13.15 ± 0.89
0.06
ES60I
23.90 ± 1.54
0.06
20.65 ± 1.78
0.08
14.92 ± 1.42
0.09
*Mean of three separate observations ± standard deviation. SD: standard deviation. VS: mean vesicle size in μm. PI: polydispersity index obtained as PI = (SD/VS).
