International Scholarly Research Notices / 2012 / Article / Tab 1

Review Article

New Concepts in Median Nail Dystrophy, Onychomycosis, and Hand, Foot, and Mouth Disease Nail Pathology

Table 1

Summary of in vitro and in vivo studies demonstrating efficacy of laser therapy in the treatment of onychomycosis.

StudyIn vitro or in vivoLaser modelOutcome

Vural et al. [19]In vitroQ-switched Nd:YAG laser 532-nm and 1064-nm wavelengthsInhibition of fungal colony growth
Manevitch et al. [20]In vitroFemtosecond infrared titanium sapphireComplete clearance of T. rubrum infected nail clippings after 4 weeks
Kozarev and Mitrovica [21]In vivo25-millisecond pulsed Nd:YAG laser 1064 nm wavelength100% clearance in 42 nails after 3 weeks of treatment
Hochman [22]In vivo0.65-millisecond pulsed Nd:YAG laser 1064 nm7/8 cleared after 9 weeks of treatment
Landsman et al. [23]In vivoDual-wavelength near-infrared diode laser with 830-nm and 970-nm wavelengths22/26 demonstrated improvement after 4 months of treatment

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