Summary of in vitro and in vivo studies demonstrating efficacy of laser therapy in the treatment of onychomycosis.
|Study||In vitro or in vivo||Laser model||Outcome|
|Vural et al. ||In vitro||Q-switched Nd:YAG laser 532-nm and 1064-nm wavelengths||Inhibition of fungal colony growth|
|Manevitch et al. ||In vitro||Femtosecond infrared titanium sapphire||Complete clearance of T. rubrum infected nail clippings after 4 weeks|
|Kozarev and Mitrovica ||In vivo||25-millisecond pulsed Nd:YAG laser 1064 nm wavelength||100% clearance in 42 nails after 3 weeks of treatment|
|Hochman ||In vivo||0.65-millisecond pulsed Nd:YAG laser 1064 nm||7/8 cleared after 9 weeks of treatment|
|Landsman et al. ||In vivo||Dual-wavelength near-infrared diode laser with 830-nm and 970-nm wavelengths||22/26 demonstrated improvement after 4 months of treatment|