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ISRN Biochemistry
Volume 2012 (2012), Article ID 707586, 6 pages
Research Article

Withaferin A Induces Proteasome-Dependent Degradation of Breast Cancer Susceptibility Gene 1 and Heat Shock Factor 1 Proteins in Breast Cancer Cells

1Department of Surgery, University of Kansas School of Medicine, Kansas City, KS 66160, USA
2Department of Medicinal Chemistry, The University of Kansas, Lawrence, KS 66045, USA

Received 23 May 2012; Accepted 1 August 2012

Academic Editors: A. Azem, A.-M. Lambeir, B. Penke, and A. Tavares

Copyright © 2012 Xuan Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [3 citations]

The following is the list of published articles that have cited the current article.

  • Tania Das, Kumar Singha Roy, Tulika Chakrabarti, Sibabrata Mukhopadhyay, and Susanta Roychoudhury, “Withaferin A modulates the Spindle Assembly Checkpoint by degradation of Mad2–Cdc20 complex in colorectal cancer cell lines,” Biochemical Pharmacology, 2014. View at Publisher · View at Google Scholar
  • Juan M. Sonego, Ezequiel M. Rivero, Lucía Gargiulo, Isabel Lüthy, Lautaro D. Alvarez, Adriana S. Veleiro, and Gerardo Burton, “Synthesis and biological evaluation of salpichrolide analogs as antiestrogenic agents,” European Journal of Medicinal Chemistry, vol. 82, pp. 233–241, 2014. View at Publisher · View at Google Scholar
  • In-Chul Lee, and Bu Choi, “Withaferin-A—A Natural Anticancer Agent with Pleitropic Mechanisms of Action,” International Journal of Molecular Sciences, vol. 17, no. 3, pp. 290, 2016. View at Publisher · View at Google Scholar