Pharmacological Evaluation and Docking Studies of 3-Thiadiazolyl- and Thioxo-1,2,4-triazolylcoumarin Derivatives as Cholinesterase Inhibitors

<table>Lineweavere-Burk reciprocal plots of inhibition kinetics of (a) acetylcholinesterase and (b) butyrylcholinesterase by the compound <b>4b.</b> Changes in the initial velocities of the reaction were measured at different concentrations of the inhibitors (from 0–100 and 0–5 nM for acetyl and butyrylcholinesterase, resp.) by using substrates ATCI and BTCCl.</table>

International Scholarly Research Notices

fig2

Figure 2

Figure 2: Pharmacological Evaluation and Docking Studies of 3-Thiadiazolyl- and Thioxo-1,2,4-triazolylcoumarin Derivatives as Cholinesterase Inhibitors 

Figure 2 | Pharmacological Evaluation and Docking Studies of 3-Thiadiazolyl- and Thioxo-1,2,4-triazolylcoumarin Derivatives as Cholinesterase Inhibitors 