The Toxic Effects of Polychemotherapy onto the Liver Are Accelerated by the Upregulated MDR of Lymphosarcoma
Figure 6
P-Glycoprotein expression on the surface of hepatocyte membrane in the liver. Immunohistochemical staining of paraffin sections of the liver of healthy mice (a) and mice bearing RLS40 after multiple polychemotherapy according to Scheme 1 (b). Quantification of the results of immunohistochemical staining (c). Expression levels correspond to the following scale: 0 no expression, 1+ weak expression, 2+ moderate expression, and 3+ strong expression.
