Table of Contents
ISRN Optics
Volume 2012 (2012), Article ID 735231, 13 pages
http://dx.doi.org/10.5402/2012/735231
Research Article

Validation of an XCT/fDOT System on Mice

1CEA, LETI, MINATEC, 17 Rue des Martyrs, 38054 Grenoble Cedex 9, France
2SCANCO Medical AG, Fabrikweg 2, 8306 Brüttisellen, Switzerland
3INSERM U823, Institut Albert Bonniot, 38706 La Tronche Cedex, France
4Institute for Biomedical Engineering, University and ETH Zurich, Wolfgang-Pauli-Strasse 10, 8093 Zürich, Switzerland

Received 12 December 2011; Accepted 22 January 2012

Academic Editors: S. Liu and R. J. Zawadzki

Copyright © 2012 Anne Koenig et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. Ntziachristos, E. A. Schellenberger, J. Ripoll et al., “Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate,” Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 33, pp. 12294–12299, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. J. O. Deguchi, M. Aikawa, C. H. Tung et al., “Inflammation in atherosclerosis—visualizing matrix metalloproteinase action in macrophages in vivo,” Circulation, vol. 114, no. 1, pp. 55–62, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. K. Licha and C. Olbrich, “Optical imaging in drug discovery and diagnostic applications,” Advanced Drug Delivery Reviews, vol. 57, no. 8, pp. 1087–1108, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. L. Sancey, S. Dufort, V. Josserand et al., “Drug development in oncology assisted by noninvasive optical imaging,” International Journal of Pharmaceutics, vol. 379, no. 2, pp. 309–316, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Koenig, L. Hervé, G. Gonon et al., “Fluorescence diffuse optical tomography for free-space and multifluorophore studies,” Journal of Biomedical Optics, vol. 15, no. 1, Article ID 016016, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. V. Ntziachristos, A. G. Yodh, M. D. Schnall, and B. Chance, “MRI-guided diffuse optical spectroscopy of malignant and benign breast lesions,” Neoplasia, vol. 4, no. 4, pp. 347–354, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. F. Stuker, C. Baltes, K. Dikaiou et al., “Hybrid small animal imaging system combining magnetic resonance imaging with fluorescence tomography using single photon avalanche diode detectors,” IEEE Transactions on Medical Imaging, vol. 30, no. 6, pp. 1265–1273, 2011. View at Publisher · View at Google Scholar
  8. Q. Zhu, T. Durduran, V. Ntziachristos, M. Holboke, and A. G. Yodh, “Imager that combines near-infrared diffusive light and ultrasound,” Optics Letters, vol. 24, no. 15, pp. 1050–1052, 1999. View at Google Scholar · View at Scopus
  9. J. Boutet, L. Herve, M. Debourdeau et al., “Bimodal ultrasound and fluorescence approach for prostate cancer diagnosis,” Journal of Biomedical Optics, vol. 14, no. 6, Article ID 064001, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. R. G. Blasberg, “In vivo molecular-genetic imaging: multi-modality nuclear and optical combinations,” Nuclear Medicine and Biology, vol. 30, no. 8, pp. 879–888, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. A. da Silva, T. Bordy, M. Debourdeau, J. M. Dinten, P. Peltié, and P. Rizo, “Coupling X-ray and optical tomography systems for in vivo examination of small animals,” in Proceedings of the 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. 2007, pp. 3335–3338, Lyon, France, 2007. View at Publisher · View at Google Scholar
  12. W. C. Barber, Y. Lin, O. Nalcioglu, J. S. Iwanczyk, N. E. Hartsough, and G. Gulsen, “Combined fluorescence and X-ray tomography for quantitative in vivo detection of fluorophore,” Technology in Cancer Research and Treatment, vol. 9, no. 1, pp. 45–51, 2010. View at Google Scholar · View at Scopus
  13. D. Kepshire, N. Mincu, M. Hutchins et al., “A microcomputed tomography guided fluorescence tomography system for small animal molecular imaging,” Review of Scientific Instruments, vol. 80, no. 4, Article ID 043701, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. R. B. Schulz, A. Ale, A. Sarantopoulos et al., “Hybrid system for simultaneous fluorescence and X-ray computed tomography,” IEEE Transactions on Medical Imaging, vol. 29, no. 2, pp. 465–473, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. N. Deliolanis, T. Lasser, D. Hyde, A. Soubret, J. Ripoll, and V. Ntziachristos, “Free-space fluorescence molecular tomography utilizing 360° geometry projections,” Optics Letters, vol. 32, no. 4, pp. 382–384, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Koenig, L. Hervé, J. Boutet et al., “Fluorescence diffuse optical tomographic system for arbitrary shaped small animals,” in Proceedings of the 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, (ISBI '08), pp. 1593–1596, Paris, Farnce, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. A. Koenig, A. Planat-Chrétien, J. G. Coutard et al., “Development of a bi-modality XCT-DOT instrument,” in Progress in Biomedical Optics and Imaging (BIOS '10), F. S. Azar and X. Intes, Eds., vol. 7557 of Proceedings of SPIE, p. 755709, 2010, Edited by Azar, Fred S., Intes, Xavier. View at Publisher · View at Google Scholar
  18. A. Koenig, L. Hervé, A. da Silva et al., “Whole body small animal examination with a diffuse optical tomography instrument,” Nuclear Instruments and Methods in Physics Research A, vol. 571, no. 1-2, pp. 56–59, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Boutet, A. Koenig, L. Hervé et al., “Optical tomograph optimized for tumor detection inside highly absorbent organs,” Optical Engineering, vol. 50, no. 5, Article ID 053203, 2011. View at Publisher · View at Google Scholar
  20. http://www.scanco.ch.
  21. I. A. Feldkamp, L. C. Davis, and J. W. Kress, “Practical cone-beam algorithm,” Journal of the Optical Society of America A, vol. 1, no. 6, pp. 612–619, 1984. View at Google Scholar · View at Scopus
  22. A. Planat-Chrétien, A. Koenig, J. G. Coutard, L. Hervé, M. Brambilla, and J. M. Dinten, “Toward absolute quantification in CW-FDOT systems: use of a priori information,” in European Conferences on Biomedical Optics and Imaging (ECBO '11), vol. 8088 of Proceedings of SPIE, Munich, Germany, May 2011. View at Publisher · View at Google Scholar
  23. L. Hervé, A. Koenig, A. da Silva et al., “Noncontact fluorescence diffuse optical tomography of heterogeneous media,” Applied Optics, vol. 46, no. 22, pp. 4896–4906, 2007. View at Publisher · View at Google Scholar · View at Scopus
  24. L. Hervé, A. Koenig, and J.-M. Dinten, “Non-uniqueness in fluorescence-enhanced continuous wave diffuse optical tomography,” Journal of Optics, vol. 13, no. 1, Article ID 015702, 2011. View at Publisher · View at Google Scholar
  25. R. C. Haskell, L. O. Svaasand, T. T. Tsay, T. C. Feng, M. S. McAdams, and B. J. Tromberg, “Boundary conditions for the diffusion equation in radiative transfer,” Journal of the Optical Society of America A, vol. 11, no. 10, pp. 2727–2741, 1994. View at Google Scholar · View at Scopus
  26. Y. Zhang, D. H. Brooks, and D. A. Boas, “A haemodynamic response function model in spatio-temporal diffuse optical tomography,” Physics in Medicine and Biology, vol. 50, no. 19, pp. 4625–4644, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. M. J. Holboke, B. J. Tromberg, X. Li et al., “Three-dimensional diffuse optical mammography with ultrasound localization in a human subject,” Journal of Biomedical Optics, vol. 5, no. 2, pp. 237–247, 2000. View at Publisher · View at Google Scholar · View at Scopus
  28. B. W. Pogue, T. O. McBride, J. Prewitt, U. L. Osterberg, and K. D. Paulsen, “Spatially variant regularization improves diffuse optical tomography,” Applied Optics, vol. 38, no. 13, pp. 2950–2961, 1999. View at Google Scholar · View at Scopus
  29. Y. Lin, H. Yan, O. Nalcioglu, and G. Gulsen, “Quantitative fluorescence tomography with functional and structural a priori information,” Applied Optics, vol. 48, no. 7, pp. 1328–1336, 2009. View at Publisher · View at Google Scholar · View at Scopus