A Comparative Analysis of Mast Cell Quantification in Five Common Dermatoses: Lichen Simplex Chronicus, Psoriasis, Lichen Planus, Lupus, and Insect Bite/Allergic Contact Dermatitis/Nummular Dermatitis

Table 2

Mast cells. It shows the outcome variable—the number of mast cells. Overall, the distribution of mast cells is different across the two methods (𝑃<.0001). The median number of mast cells revealed using C-Kit method was 17.5 compared to the median number of mast cells revealed using T-Blue method. The distribution of mast cells is same across the two methods for lichen simplex chronicus (𝑃=0.110).

Characteristic	Median (p25, p75)^1	𝑃 value^2
Group
C-Kit	17.5 (11.8; 22.5)
T-Blue	3.8 (2.5; 7.0)	<.0001*
Psoriasis
C-Kit	16.5 (16.0; 20.5)
T-Blue	2.5 (1.0; 4.0)	0.012*
Lichen simplex chronicus
C-Kit	14.3 (10.0; 35.0)
T-Blue	7.8 (6.0; 12.8)	0.110
Lupus
C-Kit	12.5 (6.0; 17.5)
T-Blue	5.5 (3.5; 6.0)	0.024*
Lichen planus
C-Kit	22.5 (20.0; 22.5)
T-Blue	3.5 (0.5; 7.5)	0.036*
Allergic/nummular/insect
C-Kit	17.5 (15.0; 22.5)
T-Blue	3.0 (2.5; 3.0)	0.009*

¹p25 represents the 25th percentile; p75 represents the 75th percentile.
²Mann-Whitney 𝑈 test.
*indicates significance at 0.05 level of significance.