Clinical Study

Laparoscopic Risk-Reducing Salpingo-Oophorectomy: The Brigham and Women's Experience

Table 2

Demographic and clinical characteristics of the study population by genetic status.

Overall* BRCA-1 BRCA-2 BRCA1/2 HBOC ๐‘ƒ

Age
๐‘ (%) 358/358 (100%) 147 (41.1%) 126 (35.2%) 4 (1.1%) 81 (22.6%) ANOVA ๐‘ƒ -value 0.0005
Mean age (SD) 48.1 (9.2)45.9 (8.4)49.9 (10.2)42.8 (9.7)49.7 (7.9)

BMI
๐‘ (%) 349/349 (100%) 145 (41.5%) 124 (35.5%) 4 (1.1%) 76 (21.8%) ANOVA ๐‘ƒ -value 0.84
Mean BMI (SD)26.0 (5.2)26.1 (5.1)26.1 (5.6)25.8 (4.9)25.5 (5.1)

Pre-menopausal status
๐‘ (%) 188/356 (52.8%) 92 (62.6%) 59 (46.8%) 1 (25.0%) 36 (45.6%) Fisherโ€™s exact ๐‘ƒ -value 0.01

Positive previous surgical history
๐‘ (%) 173/357 (48.5%) 70 (47.6%) 63 (50.4%) 1 (25.0%) 39 (48.2%) Fisherโ€™s exact ๐‘ƒ -value 0.83

Previous diagnosis of breast cancer
๐‘ (%) 189/357 (52.9%) 79 (53.7%) 67 (53.6%) 2 (50.0%) 41 (50.6%) Fisherโ€™s exact ๐‘ƒ -value 0.96

*Refers to the total number of patients (pts) with nonmissing data for the indicated variable.
**All variables as assessed by the time of RRSO.