Variable Resistance of RMS to Interferon γ Signaling
Figure 6
Transcriptional increase of target genes after IFNγ treatment. Relative mRNA expression of MHCI (a) and MHCII (b) in RMS cells and HT29 control cells as well as AChR (c) and γ (d) in RMS cells after IFNγ treatment was determined by qRT-PCR, normalized to GAPDH specific signals and compared to nontreated cells. Expression of each of the respective nontreated cells was arbitrarily set as 1.0. RQ, relative quotient. Data represent the mean ± SEM of one representative experiment out of three. Beware of different scales used for HT29 cells (light grey bar) in (b).