Review Article

A New Strategy to Find Targets for Anticancer Therapy: Chemokine CXCL14/BRAK Is a Multifunctional Tumor Suppressor for Head and Neck Squamous Cell Carcinoma

Figure 8

EGF downregulates expression of CXCL14/BRAK, a multifunctional tumor suppressor. (a) EGF stimulates tumor progression by regulating expression of tumor-progression factors in addition to CXCL14/BRAK. Upward red arrows indicate upregulation of the gene expression and downward blue arrows indicate downregulation of the gene expression. (b) CXCL14/BRAK is a multifunctional tumor suppressor.
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(a)
797619.fig.008b
(b)