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ISRN Oncology
Volume 2012 (2012), Article ID 809370, 9 pages
Research Article

A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing

1Department of Otolaryngology-Head and Neck Surgery, Western University, Victoria Hospital, London Health Science Centre, Room B3-431A, 800 Commissioners Road East, London, ON, Canada N6A 5W9
2London Regional Cancer Program, London, ON, Canada N6A 4L6
3Lawson Health Research Institute, London, ON, Canada N6C 2R5
4Department of Oncology, Western University, London, ON, Canada N6A 4L6
5Department of Pathology, Western University, London, ON, Canada N6A 5C1
6Informatics and Biocomputing Platform, Ontario Institute for Cancer Research, Toronto, ON, Canada M5G 0A3
7Department of Biostatistics, University of Toronto, Toronto, ON, Canada M5T 3M7
8Department of Microbiology and Immunology, Western University, London, ON, Canada N6A 5C1
9Department of Radiation Oncology (MAASTRO), GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, P.O. Box 616, 6200 MD Maastricht, The Netherlands
10Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada M5G 2M9

Received 31 October 2012; Accepted 22 November 2012

Academic Editors: R.-J. Bensadoun and H.-W. Lo

Copyright © 2012 Anthony C. Nichols et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Tables S1 and S2.

The supplementary tables provide a complete listing of the mutations identified by our bioinformatics pipeline in the HPV-positive (Table S1) and HPV-negative (Table S2) tumor samples but not in the matched blood samples. This listing includes mutations found in both coding and non-coding regions.

  1. Supplementary Table S1
  2. Supplementary Table S2