A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing

Table 2

Patient demographics.

	Patient 1	Patient 2
	HPV positive	HPV negative
Age	49	81
Gender	Male	Female
Primary site	Tonsil	Oral tongue
Stage	T2N0	T2N0
Smoking	Nonsmoker	50 pack years
Alcohol	Nondrinker	Rare
Differentiation	Moderate	Moderate to poorly
Adverse features	Perineural invasion	Perineural invasion
p16	Positive	Negative
HPV	Positive	Negative
Treatment	TORS + ND	Transoral resection, ND, RFFF

HPV: human papillomavirus, TORS: transoral robotic surgery, ND: neck dissection, and RFFF: radial forearm free flap.