Research Article

Differential Expression Analysis for RNA-Seq Data

Table 1

Assessing variability across replicates using the likelihood ratio test on 17708 genes.

No. of replicates Percentage (number) of genes with similar count at
different levels
1% 2.5% 5% 10%

2 98.8 (17506) 97.5 (17282) 94.7 (16782) 89.2 (15809)
3 98.4 (17425) 96.6 (17111) 93.9 (16637) 88.5 (15674)
4 97.1 (17202) 94.8 (16795) 91.5 (16209) 85.8 (15197)
5 96.2 (17037) 93.5 (16563) 90.1 (15970) 84.0 (14876)